Joint Fluid Analysis Guide

Monosodium Urate (MSU) crystals appear as negatively birefringent needle shaped crystals under red compensated polarized light microscopy. Appearance of a typical MSU fluid (white arrow shows orientation of red compensator):

Monosodium Urate (MSU) crystals

 

 

 

 

 

 

Close-up View:

Monosodium Urate (MSU) crystals

 

MSU Tophus
MSU Tophus

Calcium Pyrophosphate Dihydrate (CPPD) crystals appear as positively birefringent rhomboidal crystals under red compensated polarized light microscopy.  Appearance of a typical CPPD fluid (white arrow shows orientation of red compensator):

Calcium Pyrophosphate Dihydrate (CPPD) crystals

 

 

 

 

 

Close-up View: 
Calcium Pyrophosphate Dihydrate (CPPD) crystals

Cholesterol crystals appear as positively birefringent planar crystals with notched corners under red compensated polarized light microscopy.

Cholesterol crystals

Lipid Liquid crystals appear as positively birefringent tiny spheres under red compensated polarized light microscopy.

Lipid Liquid crystals

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Page Updated 12/15/2014
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