Basic and Translational Science

Degrees Offered
Doctor of Philosophy

Direct entrance into Basic and Translational Science Program not available. Enrolled Basic Science PhD seekers may apply to this program in their third year of study.

Program Description
The program builds on a strong foundation of core basic science knowledge and develops competencies associated with successful scientific innovation and research in a multidisciplinary collaborative learning environment. In this program, students are trained to think broadly about the clinical applications of the basic sciences and to carry out research bridging the gap between basic science and clinical practice. Students will come into graduate school through the Interdisciplinary Program in Biomedical Sciences (IDP), Neurosciences Doctoral Program, Physiology Graduate Program or Biophysics Graduate Program in Imaging.

Program Admissions Requirements
In addition to the general Graduate School admission requirements, this program has additional specific requirements.

Basic Science PhD seekers who are in good academic standing may express interest in the program near the end of the first year when a basic science advisor is chosen. If the advisor chosen is willing to help you pursue the translation component you will later apply to the BTS Program.

Program Degree Requirements
Students will satisfy the PhD requirements of their Basic Science Department and those of the Translational Science portion of the program.

Six credits of advance coursework to be determined by the basic science department, counted toward both the departmental requirements and the BTS requirements.

Six credits of coursework selected from a menu of Clinical Translational Courses. “Boundaries of Science and Medical Practice” is required, as is a Biostatistics course.

Within the 12-credit requirement, a pathophysiological component must be present.

Required Course

21150 Boundaries of Science and Medical Practice. 1 credit.
Translational Science will be explored through term-based learning with class discussion of assigned cases. At the end of the course, the students will describe and analyze the use of appropriate clinical and translational research techniques, evidence-based medicine and outcomes research methods; identify gaps between basic science knowledge and clinical practice for specific clinical questions pertinent to their area of research; propose the steps needed to apply basic science knowledge to outline possible experiments that are feasible and compliant with regulatory and ethical issues; and identify significant clinical questions/hypotheses that would benefit from translational research programs.

Biostatistics Course Requirement 
(at least 1 credit) See course description within specific program.

04200 Biostatistics I. 3 credits. (see Biostatistics program listing)
18204 Introduction to Biostatistics. 3 credits. (see Public Health program listing)

Pathophysiology Component Requirement
(at least 1 credit)

12206 Integrated Graduate Neuroscience—4 Credits
03251 Free Radicals in Biology—3 Credits
31152 Human Development—1 Credit
31153 Cell Tissue Biology—4 Credits
12205 Integrated Neuroscience—6 Credits
31207 Introduction to Neuroscience—2 Credits
31210 Advanced Clinical Human Anatomy—1-3 Credits
31212 Developmental and Stem Cell Biology—3 Credits
31257 Biology of Vision—3 Credits
25259 Mucosal Immunity—1 Credit
25260 Mucosal Pathogenesis—1 Credit
25261 Bacterial Toxin-Mucosal Cell Interactions—1 Credit
25262 Tumor Immunology—1 Credit
25263 Signaling in the Immune System—1 Credit
25264 Developmental Immunology—1 Credit
25265 Immunological Tolerance—1 Credit
25266 Clinical Immunology—1 Credit
07202 Survey of Pharmacology—3 Credits
08210 Endocrine Regulation and Common Disease—1 Credit
08212 Critical Reading in Respiratory Physiology—1 Credit
08253 Advanced Renal Physiology—1 Credit
08273 Special Topics in Neuroscience—1 Credit

Elective Courses

All elective courses for the Clinical and Translational Science MS will be available to students in the Basic and Translational Science PhD Program.
Six credits of coursework to be selected.


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Medical College of Wisconsin
Graduate School of Biomedical Sciences
8701 Watertown Plank Road
Milwaukee, WI 53226-0509

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MCW Basic & Translational Science News

Vision scientists to explore causes of vision loss in albinism

Jan. 12 - The Medical College of Wisconsin (MCW) has received a four-year, $2 million grant from the National Institutes of Health’s National Eye Institute to study the specific parts of the visual system responsible for vision loss in albinism.

Lack of Sleep Can Cause Secretion of Molecule that Stokes Hunger

Jan. 6 - In a round-up article on sleep research studies nationwide, the Buffalo News reports on collaborative research by MCW and the University of Chicago that found that lack of sleep can cause the body to secrete a molecule called 2-AG, which stokes hunger. Buffalo News

Dr. Everson Discovers that Sleep Deprivation Causes Cellular Damage

Dec. 15 - Carol Everson, PhD is lead author of a study published in Sleep that found that sleep deprivation causes damage to cells, especially in the liver, lung, and small intestine. Medical News Today and Milwaukee Courier

MSTP Student Receives $180,000 NIH Grant to Study Development of Diabetes

Dec. 9 - Zach Shaheen, an MCW Medical Scientist Training Program (MSTP) student, received a four-year, $180,000 National Institute of Diabetes and Digestive and Kidney Diseases grant to investigate the pancreatic immune response involved in the development of insulin-dependent diabetes mellitus during a viral infection. MSTP students are enrolled in both MCW’s Medical School and Graduate School. Wauwatosa Now

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Page Updated 01/08/2015