ISMRM Abstracts

For an overview of current MRI research in the Department of Biophysics, please see the following recent abstracts authored by Biophysics faculty and students and accepted by the International Society for Magnetic Resonance in Medicine for presentation at its annual meeting.

 2013: ISMRM 21st Scientific Meeting & Exhibition | Salt Lake City, Utah

Image Reconstruction

A Complex-Valued Algorithm That is Superior the Standard Magnitude-Only Algorithm for Separation of Two Simultaneously Excited Complex-Valued Images from One Complex-Valued Aliased Image. Rowe DB, Hyde JS, Jesmanowicz A, Nencka AS Proc. Intl. Soc. Magn. Reson. Med., 20:123, Salt Lake City, Utah, USA, 2013.

fMRI of Brain Disorders

Repeatability of Standardized and Normalized RCBV in Patients with Newly Diagnosed GMB. Melissa Prah, Eric Paulson, Dominique Jennings, Elizabeth Gerstner, Tracy T. Batchelor, Steven M. Stufflebeam, Kathleen Schmainda

The Altered Value-Based Intrinsic Network and Its Association with Impulsive Behavior in Abstinent Heroin Dependent Subjects. Tianye Zhai, Tianye Zhai, Chunming Xie, Zheng Yang, Shi-Jiang Li

Imaging of Psychiatric Disorders

Neural Basis of the Association Between Remitted Geriatric Depression and APOE &[epsilon]4 Allele in the Nondemented Elderly. Hao Shu, Yonggui Yuan, Chunming Xie, Feng Bai, Jiayong You, Lingjiang Li, Shi-Jiang Li, Zhijun, Zhang

Functional Connectivity: Acquisitions & Artifacts

The Application of Accelerated Functional Connectivity Magnetic Resonance Imaging to Study the Higher Frequency Band Resting State Functional Connectivity (R-fcMRI) and the Improvement for the Individual rfcMRI Repeatability. Guangyu Chen, Andrew S. Nencka, Guangyu Chen, Shi-Jiang Li

Temporal Processing of fMRI Data Induces Functional Correlations and Potentially Alters Functional Activations. Karaman MM, Nencka AS, Rowe DB  Proc. Intl. Soc. Magn. Reson. Med., 20:2232, Salt Lake City, Utah, USA, 2013.

Artificial Correlations Induced by SENSE and GRAPPA Corrupt fcMRI Conclusions
Iain P. Bruce, Daniel B. Rowe

Functional Connectivity Analysis

Power-Law Functional Organizations of the Brain in Wake, Anesthesia, and Vegetative State. Xiaolin Liu, B. Douglas Ward, Shi-Jiang Li, Anthony Hudetz

Animal fMRI Studies

C7 Nerve Root Sensory Mapping: A 9.4T Bold Functional MRI Investigation
Jacques Machol IV, Rupeng Li2, Patrick Hettinger, Nicholas Flugstad, Ji-Geng Yan, Hani Matloub, James S. Hyde

Image Reconstruction and Analysis

Efficient Algorithm of B0 Drift Correction in Time Series of Phase Images. Andrzej Jesmanowicz

Novel RF Coils

Technology Development for Sub-0.3 Mm Voxel Functional Imaging of the Murine Forepaw Barrel Subfield at 400MHz (9.4T). Phillip D. Bishop, Jason W. Sidabras, Andrzej Jesmanowicz, Rupeng Li, James S. Hyde

Advanced Imaging of Dementia

Comparing Differences in Alzheimer's Disease Classification Between Structural and Resting-State Functional MRI Biomarkers. Guangyu Chen, Chunming Xie, Guangyu Chen, Wenjun Li, B. Douglas Ward, Jennifer L. Jones, Malgorzata Franczak, Piero G. Antuono, Shi-Jiang Li

Resting State Connectivity: Applications

Reliability of Detecting Functional Connectivity Changes in Alzheimer's Disease.
Guangyu Chen, Chunming Xie, Guangyu Chen, Wenjun Li, B. Douglas Ward, Jennifer L. Jones, Malgorzata Franczak, Piero G. Antuono, Shi-Jiang Li

fMRI Acquisition Methods

Stronger Brain Functional Connectivity Revealed by Multi-Band Acquisition of FMRI. Zhan Xu, Guangyu Chen, Andrew S. Nencka, Shi-Jiang Li

fMRI:  Analysis of Activation

Incorporation of Gray Matter T1 and T2* Improves Brain Activation Statistics in fMRI. Karaman MM, Bruce IP, Rowe DB:  Proc. Intl. Soc. Magn. Reson. Med., 20:2285, Salt Lake City, Utah, USA, 2013.

Arrays & Array Technology

SENSE Induced Correlations are Used to Optimize RF Coil Design for Specific fcMRI Studies. Bruce IP, Muftuler LT, Rowe DB:  Accepted to Proc. Intl. Soc. Magn. Reson. Med., 20:2733, Salt Lake City, Utah, USA, 2013.

 2012: ISMRM 20th Scientific Meeting & Exhibition, SMRT 21st Annual Meeting | Melbourne, Australia

Brain Tumor Imaging - Diagnosis & Response To Therapy:

Precise Ex-Vivo Histological Validation of Heightened Cellularity in Regions of Dark ADC in Three Cases of High-Grade Glioma. Peter S. LaViolette, Elizabeth J. Cochran, Alex D. Cohen, Mona Al-Gizawiy, Scott D. Rand, Jennifer Connelly, Mark G. Malkin, Wade M. Mueller, Kathleen M. Schmainda

Clinical Diffusion:

Altered White Matter Microstructure for Cognitive Impairment Associated with First-Episode Drug-Naive Late-Onset Depression: A 6-Month Follow-Up Study with Diffusion Tensor Imaging. Daniel Han-En Chang, Huali Wang, Na Zhang, Huishu Yuan, Xin Yu, L. Tugan Muftuler, Min-Ying Su.

Brain Tumor Imaging: Diagnosis & Response to Therapy:

Contrast Leakage in High Grade Glioma Measured with Independent Component Analysis of Dynamic Susceptibility Contrast MRI. Peter S. LaViolette, Alex D. Cohen, Kathleen M. Schmainda

Ex-Vivo Infiltrative Brain Tumor Histologically Correlates with Decreased ADC and Increased RCBV as Measured with Functional Diffusion and Perfusion Maps. Peter S. LaViolette, Melissa A. Prah, Mona Al-Gizawiy, Elizabeth J. Cochran, Scott D. Rand, Jennifer Connelly, Mark G. Malkin, Wade M. Mueller, Kathleen M. Schmainda

Animal Models of Brain Disease Other Than Stroke:

Precise Correlation of Relative Cerebral Blood Volume & Von Willebrand Factor Stained Histology Using the HistToMRI Toolbox. Peter S. LaViolette, Andrew C. Discolo, Kimberly A. Pechman, Kathleen M. Schmainda

Non-invasive Perfusion Imaging in Animals:

IVIM and DSC Metrics Are Heightened in Rat C6 Brain Tumors. Alexander David Cohen, Peter S. LaViolette, Kimberly Pechman, Kathleen M. Schmainda,

fMRI Analysis:

Voxel-Wise Tissue Segmentation and Partial Volume Quantification in Experimental EPI Space to Inform FMRI and fcMRI Analysis. Daniel L. Shefchik, Andrew S. Nencka, Andrzej Jesmanowicz, James S. Hyde

fMRI Connectivity Analysis:

T1/T2 Ratio Maps for the Production of fcMRI Seed Region Based on Gray Matter Myeloarchitecture. Daniel L. Shefchik, Andrew S. Nencka, Andrzej Jesmanowicz, Edgar A. DeYoe, James S. Hyde

A Method to Determine the Necessity for Global Signal Regression in Resting-State FMRI Studies. Gang Chen, Guangyu Chen, Chunming Xie, B. Douglas Ward, Wenjun Li, Piero Antuono, Shi-Jiang Li

Human fMRI: Systems Neuroscience:

Thalamocortical Vs. Corticocortical Functional Connections During Propofol-Induced Anesthesia. Xiaolin Liu, Barney D. Ward, Shi-Jiang Li, Anthony G. Hudetz

Common and Unique Neural Regions Activated During Simple Hand Movements: Implications for Understanding Plasticity After Peripheral Nerve Damage. Rebecca D. Ray, Michelle Johnson, Christopher Pawela

fMRI: Animal Neuroscience:

fMRI/fcMRI Investigation Showing Cortical and Subcortical Pathways Involving in Phrenic Nerve Activation and Respiration Control in Rats Under 9.4Tesla. Rupeng Li, Nicholas Flugstad, Xiping Liu, Christopher Pawela, Ji-Geng Yan, Hani S. Matloub, James S. Hyde

Plasticity of the Rat Sensory Cortex at 9.4T Demonstrated in a Survival Model of Brachial Plexus Injury and Repair with Contralateral C7 Nerve Transfer. Nicholas A. Flugstad, Jack B. Stephenson, Rupeng Li, Ji-Geng Yan, Christopher Pawela, Hani S. Matloub, James S. Hyde

Parallel MRI:

Single-Coil Two-Fold Accelerated Spin-Echo Phase-SENSE Imaging of the Rodent Brain at 9.4T. Daniel S. Shefchik, Andrzej Jesmanowicz, Matthew Budde, Andrew S. Nencka

Water/Fat Imaging:

Simultaneous EPI-Based T1, T1, and T2' Mapping. Daniel L. Shefchik, Andrew S. Nencka, Andrzej Jesmanowicz, James S. Hyde

RF: Other:

Consistent Phase Contrast Volumetric Imaging from a Set of 2D Slices. Andrzej Jesmanowicz, Robert W. Cox

Receive Efficiency & Noise Mitigation:

Software-Based Optimization of Coil Geometries for Decoupling a Pair of Loop and Fo8 Elements: Does Separation Between Coil Elements Matter? Volkan Emre Arpinar, L Tugan Muftuler

Multi-Slice N-Fold Acceleration with Scalable Digital Transmit and Receive Systems. Andrzej Jesmanowicz, William J. O’Reilly

MR Engineering: RF Coils & Systems:

Optimization and Sensitivity Analysis of Capacitive Inductive and Transformer Decoupling Schemes for RF Coil Arrays. Volkan Emre Arpinar, L Tugan Muftuler

Novel RF Coil Array Designs to Improve SNR in Dorsal Areas of the Brain. Volkan Emre Arpinar, James S. Hyde, L Tugan Muftuler

Animal Models of Brain Disease & Educational:

Long-Term Survival Study Showing Aging Effect on the Sensory Function of Peripheral Nervous System in Rats Using FMRI/fcMRI Under 9.4 Tesla. Rupeng Li, Jack B. Stephenson IV, Nicholas Flugstad, Xiping Liu, Christopher Pawela, Ji-Geng Yan, Hani S. Matloub, James S. Hyde

Psychiatric Disorders:

Altered Hippocampal Connectivity Network Associated with Impulsivity in Abstinent Heroin Addicts. Tianye Zhai, Chunming Xie, Wenjun Li, Zheng Yang, Shi-Jiang Li

Spine/Bone:

Multiparametric Analysis of the Pathophysiology and Etiology of Spinal Disc Degeneration. L. Tugan Muftuler, Vance O. Gardner3, Hon J. Yu, Dennis J. Maiman

 2011: ISMRM 19th Scientific Meeting & Exhibition, SMRT 20th Annual Meeting | Montreal, Quebec, Canada

Perfusion MRI: DSC & DCE MRI

Independent Component Analysis of Dynamic Susceptibility Contrast MRI in Brain Tumor: A New Biomarker for Measuring Tumor Perfusion Patterns
PS LaViolette, AD Cohen, SD Rand, W Mueller, KM Schmainda (Proc Intl Soc Mag Reson Med 19:789)

Cancer Animal Models - Characterization & Response

Timing of Anti-Angiogenic Therapy in Brain Tumors Using MRI Measures of Relative Cerebral Blood Volume and Apparent Diffusion Coefficient
KR Pechman, DL Donohoe, D Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 19:975)

Optimization of Combined Bevacizumab Plus Temozolomide Therapy in Brain Tumor Xenograft Models Using MRI Measures of Relative Cerebral Blood Volume
KR Pechman, DL Donohoe, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 19:976)

Non-Human fMRI

Comparing Results of Median Nerve Stimulation Between Healthy and C7 Donor Rats Utilizing BOLD fMRI at 9.4T
JB Stephenson, R Li, PC Hettinger, M Runquist, CP Pawela, J-G Yan, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 19:1582)

MR Engineering: Other

A Mechanism to Produce Translational and Rotational Motion of a Phantom Inside an MR Scanner
T Prieto, B Armstrong, M Brzeski, R Barrows, T Kusik, M Zaitsev, O Speck, T Ernst (Proc Intl Soc Mag Reson Med 19:1807)

Hardware for Animal MRI

Improving Whole Brain Coverage and Signal-To-Noise Ratio Using Novel Intra-Oral and Over Head Surface Coil Array in Rat Under 9.4T
R Li, P Bishop, A Jesmanowicz, A Nencka, JB Stephenson, CP Pawela, J-G Yan, AG Hudetz, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 19:1822)

Novel Coils & Arrays

Counter Rotating Currents Cryogenic Surface Coils
J Wosik, A Jesmanowicz, L Xue, L Xie, FSY Ip (Proc Intl Soc Mag Reson Med 19:1878)

Functional MRI in Dementia

Large-Scale Functional Network Reconfiguration Associates with its Underlying Gray Matter Atrophy in AD
W Li, G Chen, X Liu, C Xie, G Chen, BD Ward, J Goveas, J Jones, M Franczak, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 19:2192)

Characterize the Distribution and Behavior Significance of the Global Signal Measured by Resting-State Functional Connectivity in the Elderly
G Chen, C Xie, G Chen, BD Ward, W Li, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 19:2193)

Effects of Apolipoprotein E-epsilon 4 Genotype on the Functional Brain Networks Implicated in Cognition in Healthy Middle-Aged Adults
J Goveas, C Xie, G Chen, W Li, BD Ward, G Chen, J Jones, M Franczak, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 19:2194)

Different Stages in Alzheimer's Disease Target Different Large-Scale Networks, Assessed by Resting-State Functional Connectivity
G Chen, BD Ward, C Xie, W Li, G Chen, JL Jones, M Franczak, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 19:2195)

Neurodegenerative Diseases: Miscellaneous

Predict the Response of Tinnitus to Cortical Stimulation Using Resting-State Functional MRI
G Chen, BH Kopell, W Gaggl, R Ramirez, K Driesslein, S Baillet, CR Butson, S-J Li (Proc Intl Soc Mag Reson Med 19:2226)

Human Brain Tumors

T1 Intensity: An Indication of 1p 19q Deletion in Oligodendroglial Neoplasms
C Branecky, D Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 19:2422)

ADC-FLAIR Mismatch Excluding Enhancement (AFMEE): A Potential Biomarker of Tumor Invasion
PS LaViolette, AD Cohen, SD Rand, W Mueller, KM Schmainda (Proc Intl Soc Mag Reson Med 19:2423)

In-Vivo Biomarkers for Brain Tumor Vasculature and Cellularity Validated with Ex Vivo Tissue
PS LaViolette, EJ Cochran, M Al-Gizawiy, SD Rand, MG Malkin, J Connelly, W Mueller, KM Schmainda (Proc Intl Soc Mag Reson Med 19:2424)

Imaging in Psychiatric Disorders

Abnormal Resting-State Functional Connectivity as a Marker for Diagnosing and Predicting Recovery in Mild Traumatic Brain Injury
G Chen, T Hammeke, G Chen, M McCrea, BD Ward, S Miller, S-J Li (Proc Intl Soc Mag Reson Med 19:2518)

Dynamic Response Inhibition Network in Heroin Addicts Brain: Evidence from Functional Neuroimaging with Go/Go-NoGo Task
Z Yang, C Xie, Y Shao, L Fu, G Chen, W Li, J Goveas, G Chen, E Ye, L Ma, S-J Li (Proc Intl Soc Mag Reson Med 19:2524)

Decoupling of Intrinsic Insula Subregional Connectivity was Associated with Episodic Memory Decline in Amnestic Mild Cognitive Impairment
C Xie, F Bai, X Zhang, H Yu, Y Shi, Y Yuan, A Cohen, J Goveas, G Chen, W Li, G Chen, Z Yang, Z Zhang, S-J Li (Proc Intl Soc Mag Reson Med 19:2525)

Recent Advances in Image Analysis: Applications

ICA Analysis of Brachial Plexus Injury in an Animal Model Reveals Rapid Brain Plasticity in 9.4T
R Li, JB Stephenson, CP Pawela, J-G Yan, AS Nencka, AG Hudetz, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 19:2580)

Acquisition Strategies: From 3D to Spectroscopy

Two-Fold Phase Encoded SENSE Acceleration with a Single-Channel Coil
A Jesmanowicz, AS Nencka, JS Hyde (Proc Intl Soc Mag Reson Med 19:2797)

fMRI Neuroscience Methods & Applications II

Disrupted Sensory Projection and Preserved Integrative Network in Propofol-Induced Anesthesia
X Liu, KK Lauer, SM Rao, S Li, AG Hudetz (Proc Intl Soc Mag Reson Med 19:3666)

Animal fMRI

Restoration of Interhemispheric Resting-State Connectivity in S1FL Following Median Nerve Injury and Surgical Repair
CP Pawela, BB Biswal, R Li, AG Hudetz, JS Hyde (Proc Intl Soc Mag Reson Med 19:3687)

Clinical Application of Diffusion Tensor Imaging I

Predicting Effectiveness of Cortical Stimulation Therapy for Tinnitus Using DTI
W Gaggl, BH Kopell, CR Butson, RR Ramirez, S Baillet, K Driesslein, G Chen, S-J Li (Proc Intl Soc Mag Reson Med 19:4209)

Endogenous Contrast Relaxometry

Accelerated Gradient-Recalled Echo, Asymmetric Spin-Echo (GREASE-II) for Production of High-Resolution Human T1, T2, and T2* Maps
DL Shefchik, AS Nencka, A Jesmanowicz, JS Hyde (Proc Intl Soc Mag Reson Med 19:4510)

 2010: ISMRM 18th Scientific Meeting & Exhibition, SMRT 19th Annual Meeting | Stockholm, Sweden

MRI of Neural Plasticity

fcMRI Plasticity Following Rat Median Nerve Injury and Repair at 9.4T
R Li, PC Hettinger, YR Cho, CP Pawela, MA Parkins, SR Jones, J-G Yan, A Jesmanowicz, AG Hudetz, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 18:12)

Advanced Neuroimaging of Dementing Diseases

Increases in CBF by Donepezil Treatment Enhance Cingulate Functional Network Activity in Mild Alzheimer’s Disease
W Li, C Xie, J Jones, M Franczak, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 18:22)

Image Analysis Applications

3D Visualization and Quantification of Subdural Electrode Shift Due to Craniotomy Opening
PS LaViolette, A Hoyt, SD Rand, KM Schmainda, WM Mueller (Proc Intl Soc Mag Reson Med 18:61)

Young Investigator Award Presentations

Validation of Functional Diffusion Maps (FDMs) as a Biomarker for Human Glioma Cellularity
Winner: BM Ellingson, MG Malkin, SD Rand, JM Connelly, C Quincey, PS LaViolette, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 18:83)

Coil Interfacing: LNAs, Baluns & Decoupling

Spatially Quantifying Microscopic Tumor Invasion and Proliferation Using a Voxel-Wise Analytical Solution to a Glioma Growth Model and Serial Diffusion MRI
BM Ellingson, SD Rand, MG Malkin, RW Prost, JM Connelly, PS LaViolette, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 18:612)

Clinical Brain Tumor Imaging: Diagnosis to Prognosis

Functional Diffusion Maps (FDMs) Applied to FLAIR Abnormal Regions Can Detect Pseudoprogression from Recurrent Tumor in Malignant Glioma
BM Ellingson, MG Malkin, SD Rand, JM Connelly, PS LaViolette, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 18:621)

Short TE & Susceptibility MRI

Microscopic Susceptibility Variation and Transverse Relaxation for the De Facto Brain Tumor Microvasculature
D Bonekamp, E Kim, BD Ward, J Zhang, AP Pathak (Proc Intl Soc Mag Reson Med 18:703)

Drug Discovery

Levo-Tetrahydropalmatine Treatment Attenuates Heroin-Priming Induced BOLD Responses in Heroin-Dependent Rats
X Liu, Z Yang, J Xie, Q Yin, S-J Li (Proc Intl Soc Mag Reson Med 18:1065)

Outcomes: Cost Effectiveness, Etc.

Long Term Vascular Access Ports as a Means of Sedative Administration in a Rodent fMRI Survival Model
PC Hettinger, R Li, J-G Yan, HS Matloub, YR Cho, ML Runquist, CP Pawela, JS Hyde (Proc Intl Soc Mag Reson Med 18:1074)

fMRI Acquisition

Multi-Slice Two- And Four-Fold Acceleration with Single- And Eight-Channel Coils, Respectively
A Jesmanowicz, S-J Li, JS Hyde (Proc Intl Soc Mag Reson Med 18:1089)

Detecting Single Cortical Column Activation Under Super High Spatial Resolution at 9.4 T Using Single-Shot Half K-Space GR-EPI
R Li, PC Hettinger, YR Cho, CP Pawela, J-G Yan, A Jesmanowicz, AG Hudetz, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 18:1090)

fMRI Analysis Methods

A Statistical Method for Computing BOLD Activations in Multi-Echo Time fMRI Data Sets and Identifying Likely Non-BOLD Task Related Signal Change
AS Nencka, DL Shefchik, JS Hyde, A Jesmanowicz, DB Rowe (Proc Intl Soc Mag Reson Med 18:1154)

fMRI: Neuroscience

Understanding Consciousness from Information and Integration Within the Thalamocortical System
X Liu, J Zhou, AG Hudetz, S-J Li (Proc Intl Soc Mag Reson Med 18:1182)

Animal fMRI

Investigating Color Vision Using fMRI: Rodent vs. Primate
AP Salzwedel, M Mauck, J Kuchenbecker, CP Pawela, JS Hyde, M Neitz, J Neitz (Proc Intl Soc Mag Reson Med 18:1188)

The Utility of fMRI in Measuring Brain Plasticity Following Peripheral Nerve Injury
CP Pawela, BB Biswal, R Li, AG Hudetz, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 18:1200)

Refining the Sensory and Motor Ratunculus of the Rodent Upper Extremity: Evaluation of the C7 Nerve Root Using fMRI and Direct Nerve Stimulation
PC Hettinger R Li, J-G Yan, HS Matloub YR Cho, ML Runquist, CP Pawela, JS Hyde (Proc Intl Soc Mag Reson Med 18:1205)

Animal fMRI: Pharmacologic Intervention

Effects of Doxorubicin on Brain Activity and Functional Connectivity in Rats
AS Bloom, PS LaViolette, CR Chitambar, W Collier, SJ Durgerian, B Kalyanaraman, DM McAllister, CL Williams, KM Schmainda (Proc Intl Soc Mag Reson Med 18:1229)

Diffusion-Based Segmentation

Segmentation of Ischemic Lesion from Diffusion Weighted MRI and MR Apparent Diffusion Coefficient Maps
Y Attal, C Rosso, Y Samson, S Baillet (Proc Intl Soc Mag Reson Med 18:1596)

Novel Imaging Agents

Nitroxide Compound CPTO-EG as an MRI Contrast Agent
AS Nencka, X Liu, J Joseph, S-J Li, B Kalyanaraman (Proc Intl Soc Mag Reson Med 18:1904)

Imaging of Dementia & Neurodegeneration

Alteration of Integrity and Patterns of the Memory Modules in Mild Cognitive Impairment and Alzheimer’s Disease
G Chen, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 18:1950)

Dynamic Changes in Causal Strength in Memory Encoding Networks in Alzheimer’s Disease Detected by Granger Causality Analysis
G Chen, BD Ward, S-J Li (Proc Intl Soc Mag Reson Med 18:1951)

Classification of AD, MCI and Controls Using Large-Scale Network Analysis
G Chen, BD Ward, C Xie, Z Wu, W Li, J Jones, M Franczak, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 18:1960)

Amygdala Network Dysfunction Links Depressive Symptom and Memory Deficit in Elderly with Amnesic Mild Cognitive Impairment
C Xie, W Li, J Goveas, P Antuono, J Jones, G Chen, M Franczak, Z Wu, S-J Li (Proc Intl Soc Mag Reson Med 18:1996)

Clinical Brain Tumor Imaging: Anatomic, MT, SWI & Perfusion MRI

Perfusion MRI Fractional Tumor Bulk Mapping: Correlation with Multiple Stereotactic Biopsies in Recurrent GBM
LS Hu, S Liu, DS Pinnaduwage, KA Smith, P Nakaji, AC Dueck, T Jensen, JM Eschbacher, JE Heiserman, JP Karis, JP Debbins, BG Feuerstein, KM Schmainda, LC Baxter (Proc Intl Soc Mag Reson Med 18:2166)

Imaging of Brain Tumors: Techniques & Contrast Media

Delta T1 Method: An Automatic Post-Contrast ROI Selection Technique for Brain Tumors
DP Bedekar, T Jensen, SD Rand, MG Malkin, JM Connelly, KM Schmainda (Proc Intl Soc Mag Reson Med 18:2175)

Image-Guided Tissue Validation of Combined Preload Dosing and Mathematical Modeling Correction of Perfusion MRI Measures
LS Hu, LC Baxter, DS Pinnaduwage, T. Jensen, AC Dueck, JM Eschbacher, JE Heiserman, JP Karis, JP Debbins, J Placencia, S Liu, BG Feuerstein, KM Schmainda (Proc Intl Soc Mag Reson Med 18:2189)

Brain Tumor Imaging: Diffusion, MRS & High-Field Imaging

Assessment of Invasion and Recurrence in Glioblastoma Multiforme Using Diffusion Weighted MRI Edge Characteristics of Contrast Enhancing Tumor
PS LaViolette, BM Ellingson, JM Connelly, MG Malkin, SD Rand, KM Schmainda (Proc Intl Soc Mag Reson Med 18:2197)

Graded Functional Diffusion Maps (FDMs) Applied to the Whole Brain: A Sensitive Imaging Biomarker for Monitoring Brain Tumor Growth and Invasion
BM Ellingson, MG Malkin, SD Rand, JM Connelly, PS LaViolette, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 18:2200)

fMRI in Brain Diseases

Identification of Hyperactive Intrinsic Amygdala Network Associated with Impulsivity in Abstinent Heroin Addicts
C Xie, L Fu, L Ma, W Li, AD Cohen, Z Yang, SJ Li (Proc Intl Soc Mag Reson Med 18:2296)

Advanced Imaging of Spine & Spinal Cord

Diffusion Tensor MR Characteristics of Cervical Spondylosis
BM Ellingson, J-L Benae, SN Kurpad, BD Schmit, M Kocak, MC Wang (Proc Intl Soc Mag Reson Med 18:2455)

Body Diffusion

Improved Robustness with a Stretched Exponential Model for Intravoxel Incoherent Motion (IVIM) DW Signal
Y Mazaheri, DB Rowe, J Zhang, H Hricak, JA Koutcher (Proc Intl Soc Mag Reson Med 18:2655)

Tumor Therapy Response

Optimization of Combined Bevacizumab Plus Irinotecan Therapy in Brain Tumors Using MRI Measures of Relative Cerebral Blood Volume
KR Pechman, DL Donohoe, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 18:2708)

Relaxometry

Making High Resolution T2 and T2* Maps Through the Use of Accelerated Gradient-Echo Asymmetric Spin-Echo (GREASE) Pulse Sequences
DL Shefchik, AS Nencka, A Jesmanowicz, JS Hyde (Proc Intl Soc Mag Reson Med 18:2961)

Echo Planar Imaging: New Acquisition Approaches

Reducing the Effective Point Spread Function in Echo Planar Imaging Through the Use of Partial Fourier Asymmetric Spin Echo Pulse Sequences
AS Nencka, DL Shefchik, ES Paulson, A Jesmanowicz, JS Hyde (Proc Intl Soc Mag Reson Med 18:3041)

Motion Correction

Methodology for Robust Motion Correction of Complex-Valued MRI Time Series
A Hahn, DB Rowe (Proc Intl Soc Mag Reson Med 18:3051)

Image Correction: Gradients & Frequency

Iterative Space Transformation Enables the Use of Optimal Magnetic Field Correction Algorithms Using EPI-Based Field Maps
A Hahn, AS Nencka, DB Rowe (Proc Intl Soc Mag Reson Med 18:3092)

Coil Interfacing: LNAs, Baluns & Decoupling

A High Dynamic Range Receiver for Improved Diffusion Tensor Imaging
W Gaggl, A Jesmanowicz, RW Prost (Proc Intl Soc Mag Reson Med 18:3925)

DSC Perfusion

Modeling Relaxation Effects During Bolus Passage Through Leaky Vasculature Using the Finite Perturber Method
D Bonekamp, BD Ward, R Leigh, PB Barker, AP Pathak (Proc Intl Soc Mag Reson Med 18:4115)

Clinical Brain Tumor Imaging

Initial RCBV Predicts Response to Bevacizumab in Patients with High-Grade Gliomas
KM Schmainda, DP Bedekar, SD Rand, JM Connelly, MG Malkin (Proc Intl Soc Mag Reson Med 18:4288)

fMRI in Brain Disorders

Neural Underpinning from Goal-Directed Drug Seeking to Dysfunctional Stimulus-Response Habit: Increased Nucleus Accumbens – Caudate Connectivity in Heroin Addicts
AD Cohen, C Xie, W Li, TT Zhang, Z Yang, S-J Li (Proc Intl Soc Mag Reson Med 18:4459)

Prospective Motion Correction

Prospective Motion Correction for MRI with a Single Retro-Grate Reflector Target and a Single Camera
M Zaitsev, BSR Armstrong, B Andrews-Shigaki, TP Kusik, RT Barrows, K Gumus, IY Kadashevich, T Prieto, O Speck, T Ernst (Proc Intl Soc Mag Reson Med 18:5027)

Catadioptric RGR Motion Tracking for Prospective Motion Compensation in MR Acquisitions
BSR Armstrong, TP Kusik, RT Barrows, B Andrews-Shigaki, J Maclaren, M Zaitsev, O Speck, T Prieto, T Ernst (Proc Intl Soc Mag Reson Med 18:5035)

EPI Correction

In fMRI a Dual Echo Time EPI Pulse Sequence Can Induce Sources of Error in Dynamic Magnetic Field Maps
A Hahn, AS Nencka, DB Rowe (Proc Intl Soc Mag Reson Med 18:5062)

 2009: ISMRM 17th Scientific Meeting & Exhibition, SMRT 18th Annual Meeting | Honolulu, Hawaii

Functional MRI Study on Brain Plasticity Induced by Different Peripheral Nerve Injury Patterns: What Makes the Difference?
R Li, S Jones, C Pawela, M Parkins, D Shefchik, M Bosbous, J-G Yan, SS Jaradeh, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 17:125)

Functional Diffusion Maps Applied to FLAIR Abnormal Areas Are Valuable for the Clinical Monitoring of Recurrent Brain Tumors
BM Ellingson, MG Malkin, SD Rand, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 17:285)

Negative Correlation Between Medial Frontal Activity During Inhibitory Control and Impulsiveness in Abstinent Heroin Dependents: An fMRI Study
L-P Fu, Z-T Zou, S-J Li, G-H Bi, Y Wang, E-M Ye, L Ma, Z Yang (Proc Intl Soc Mag Reson Med 17:436)

Deafferentation Induced Cross-Hemispheric Brain Plasticity Detected by Resting-State Functional Connectivity Magnetic Resonance Imaging
CP Pawela, BB Biswal, R Li, AG Hudetz, JS Hyde (Proc Intl Soc Mag Reson Med 17:692)

Aricept® Treatment Enhances Hippocampal Connectivity in Subjects with Mild Alzheimer’s Disease
W Li, C Xie, Z Wu, J Jones, P Antuono, T McRae, S-J Li (Proc Intl Soc Mag Reson Med 17:734)

DSC-MRI Measures of rCBV Predict Response to Bevacizumab Treatment More Reliably Than Standard MRI in Patients with Recurrent High-Grade Gliomas
KM Schmainda, D Bedekar, SD Rand, J Connelly, S Kurpad, HG Krouwer, ES Paulson, MG Malkin (Proc Intl Soc Mag Reson Med 17:985)

Hybrid Functional Diffusion and Perfusion Maps for Evaluation of Gliomas
BM Ellingson, DP Bedekar, MG Malkin, SD Rand, A Hoyt, J Connelly, SN Kurpad, KM Schmainda (Proc Intl Soc Mag Reson Med 17:1000)

Comparison of Cytotoxic and Anti-Angiogenic Treatment Responses Using Functional Diffusion Maps in FLAIR Abnormal Regions
BM Ellingson, MG Malkin, SD Rand, A Hoyt, J Connelly, DP Bedekar, SN Kurpad, KM Schmainda (Proc Intl Soc Mag Reson Med 17:1010)

Decreased Granger Causality Strength Between the Right and Left Hippocampal Network in Patients with Alzheimer Disease
G Chen, W Li, C Xie, P Antuono, S-J Li (Proc Intl Soc Mag Reson Med 17:1100)

Global ROI-Based Functional Connectivity MRI (fcMRI) Analysis for Classification of Alzheimer’s Disease
S-J Li, BD Ward, P Antuono, Z Wu, J Jones, M-J Zhang (Proc Intl Soc Mag Reson Med 17:1101)

Detection of Changes in Functional Connectivity MRI (fcMRI) Following Aricept® Treatment in Subjects with Mild Alzheimer’s Disease
S-J Li, BD Ward, P Antuono, Z Wu, J Jones, T McRae (Proc Intl Soc Mag Reson Med 17:1102)

Enhanced Regional CBF in Patients with Mild Alzheimer’s Disease After Three Months of Aricept® Treatment
W Li, C Xie, Z Wu, J Jones, P Antuono, T McRae, S-J Li (Proc Intl Soc Mag Reson Med 17:1105)

Impaired Thalamic Functional Connectivity in Vegetative State Detected by fcMRI
J Zhou, C Xie, W Li, F Ling, S-J Li (Proc Intl Soc Mag Reson Med 17:1644)

Manipulation of BOLD Resting-State Functional Connectivity and Task Related BOLD fMRI Signal by Different Anesthetic Dosages
AG Hudetz, BB Biswal, R Li, JS Hyde, CP Pawela (Proc Intl Soc Mag Reson Med 17:1653)

Phase Regression and Dynamic B-Field Correction Reduce Global Time Series Correlations and Increase Functional Correlations
AS Nencka, AD Hahn, DB Rowe (Proc Intl Soc Mag Reson Med 17:1663)

A Peripheral Nerve Repair Model Using fMRI in Rats
MA Parkins, R Li, HS Matloub, J-G Yan, JS Hyde, CP Pawela (Proc Intl Soc Mag Reson Med 17:1680)

Anesthesia Effects on BOLD and rCBV Responses Induced by L-Tetrahydropalmatine
X Liu, Z Yang, R Li, Q Yin, S-J Li (Proc Intl Soc Mag Reson Med 17:1684)

Functional Connectivity of the Insula in Smokers
PS LaViolette, W Collier, MD Verber, KM Schmainda, L Piacentine, KL Douville, SA Claesges, SJ Durgerian, AS Bloom (Proc Intl Soc Mag Reson Med 17:1696)

An Analytic Magnitude and Phase fMRI Activation Model Applied to ASL
DB Rowe, L Hernandez-Garcia (Proc Intl Soc Mag Reson Med 17:1716)

Induced Correlation in fMRI Magnitude Data from k-Space Preprocessing
DB Rowe, AS Nencka (Proc Intl Soc Mag Reson Med 17:1721)

Analyzing Task Activated BOLD fMRI Signal Voxel Area and Intensity Measurements with Bootstrap Power Analysis
CP Pawela, BD Ward, R Li, BB Biswal, JS Hyde (Proc Intl Soc Mag Reson Med 17:1732)

Functional Connectivity and Arterial Spin Labeling in Chemotherapy Induced Cognitive Impairment (“Chemobrain”)
PS LaViolette, W Collier, KM Schmainda, L Piacentine, KL Douville, CR Chitambar, A Tran, SA Claesges, SJ Durgerian, AS Bloom (Proc Intl Soc Mag Reson Med 17:2231)

Optimization of Bevacizumab Dosing in Brain Tumors Using MRI Measures of Enhancing Tumor Volume and Relative, Cerebral Blood Volume
KR Pechman, SN Kurpad, DL Donohoe, DP Bedekar, KM Schmainda (Proc Intl Soc Mag Reson Med 17:2301)

Influence of Paramagnetic Changes in Cytochrome c on T2-Weighted MRI of G93A-SOD1 Transgenic ALS Mice
K Chandran, X Liu, D McAllister, V Roopchansingh, BD Ward, WE Antholine, J Joseph, S-J Li, B Kalyanaraman (Proc Intl Soc Mag Reson Med 17:2476)

fMRI Evaluation of Innovative Implantable Electrode for Peripheral Nerve Stimulation Animal Model
R Li, S Jones, M Parkins, C Pawela, M Bosbous, J-G Yan, HS Matloub, JS Hyde (Proc Intl Soc Mag Reson Med 17:2511)

Dynamic Magnetic Field Corrections Improve Phase-Only fMRI Activations
AD Hahn, AS Nencka, DB Rowe (Proc Intl Soc Mag Reson Med 17:2789)

Complex-Valued Voxel Thresholding Increases Image Contrast in SWI
DB Rowe, EM Haacke (Proc Intl Soc Mag Reson Med 17:2923)

Neural Correlates of Amygdala Functional Connectivity on Abstinent Heroin Addicts
Y Ma, C Xie, W Li, L Ma, Z Yang, S-J Li (Proc Intl Soc Mag Reson Med 17:3372)

Functional Connectivity Analysis of Heroin Addicts Using the Ventral Tegmental Area as a Seed
AD Cohen, C Xie, W Li, Z Yang, L Ma, S-J Li (Proc Intl Soc Mag Reson Med 17:3375)

Imaging the Functional Pathology in ApoE4 Carriers by the Hippocampus Functional Connectivity
C Xie, W Li, P Antuono, J Jones, Z Wu, S-J Li (Proc Intl Soc Mag Reson Med 17:3459)

High Resolution fcMRI: Degrees of Correlation Within the Rat Brain Finger Representation
JS Hyde, CP Pawela, BB Biswal, R Li, YR Cho (Proc Intl Soc Mag Reson Med 17:3696)

Contact Us

Department of Biophysics
Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226-0509

Phone: 414-955-4000

Fax: 414-955-6512

Directions to Department of Biophysics

MCW Campus Maps & Directions

Site Map

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
Directions & Maps
© 2014

Page Updated 11/24/2014
Top