Christopher P. Pawela, PhD

Christopher P. Pawela

Assistant Professor of Plastic Surgery
Assistant Professor of Biophysics

Phone: 414-955-5626
cpawela@mcw.edu


Education

  • Medical College of Wisconsin, PhD, 2008, MRI Biophysics
  • University of Wisconsin - Madison, MS, 2003, Chemistry
  • University of Wisconsin - Madison, BS, 1998, Bacteriology

Research Interests

Christopher Pawela, PhD, is an Assistant Professor of Plastic Surgery and Biophysics at the Medical College of Wisconsin. Dr. Pawela's goal is to develop new treatments and rehabilitation methods for peripheral (sensory) nerve injuries by learning more about how the brain responds to them.

"Peripheral nerve injuries are usually associated with traumatic accidents. Even with a successful surgical repair and a motivated patient, outcomes following these injuries can be poor. I use a variety of tools to study brain changes that occur following peripheral nerve injury and repair. These include functional magnetic resonance imaging and electroencephalographic studies of brain activity, as well as microscopic tissue studies.”

 Selected Publications
  • Pawela CP, Biswal BB, Hudetz AG, Li R, Jones SR, Cho YR, Matloub HS, Hyde JS.  Interhemispheric neuroplasticity following limb deafferentation detected by resting-state functional connectivity magnetic resonance imaging (fcMRI) and functional magnetic resonance imaging (fMRI).  Neuroimage. 2010 Feb 1;49(3):2467-78. Epub 2009 Sep 28.  Full Text

  • PAWELA CP, Biswal BB, Hudetz AG, Schulte ML, Li R, Jones SR, Cho YR, Matloub HS, Hyde JS. A protocol for use of medetomidine anesthesia in rats for extended studies using task-induced BOLD contrast and resting-state functional connectivity. NeuroImage 46:1137-1147 (2009).

  • Cho YR, Jones SR, PAWELA CP, Li R, Kao DS, Schulte ML, Runquist ML, Yan J-G, Hudetz AG, Jaradeh SS, Hyde JS, Matloub HS. Cortical brain mapping of peripheral nerves using functional magnetic resonance imaging in a rodent model. J. Reconstr. Microsurg. 24:551-557 (2008).

  • PAWELA CP, Biswal BB, Cho YR, Kao DS, Li R, Jones SR, Schulte ML, Matloub HS, Hudetz AG, Hyde JS. Resting-state functional connectivity of the rat brain. Magn. Reson. Med. 59:1021-1029 (2008).

  • PAWELA CP, Hudetz AG, Ward BD, Schulte ML, Li R, Kao DS, Mauck MC, Cho YR, Neitz J, Hyde JS. Modeling of region-specific fMRI BOLD neurovascular response functions in rat brain reveals residual differences that correlate with the differences in regional evoked potentials. NeuroImage 41:525-534 (2008).

  • Cho YR, PAWELA CP, Li R, Kao D, Schulte MS, Runquist ML, Yan J-G, Matloub HS, Jaradeh SS, Hudetz AG, Hyde JS. Refining the sensory and motor ratunculus of the rat upper extremity using fMRI and direct nerve stimulation. Magn. Reson. Med. 58:901-909 (2007).

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