Clinical and Translational Science Institute – Collaborations

Research Collaborations - Clinical and Translational Science Institute

The Clinical and Translational Science Institute (CTSI) of Southeast Wisconsin is a consortium of eight Milwaukee institutions working in partnership to cultivate biomedical research as a signature strength of the region while advancing patient care and education.
        
Member institutions are:

Medical College of Wisconsin (MCW)
Marquette University
Milwaukee School of Engineering (MSOE)
University of Wisconsin-Milwaukee (UWM)
BloodCenter of Wisconsin (BCW)
Children's Hospital and Health System
Froedtert Hospital
Zablocki VA Medical Center

In 2012, the CTSI provided support for 62 collaborative research studies through the Translational Research Unit and Pilot Awards.

These studies are conducted by investigators from the CTSI member institutions, as well as investigators from Ashland University, Concordia University, Emory University, Medical University of South Carolina, Rogers Memorial, and the University of Wisconsin- Madison.

TITLE OF STUDY

Collaborating Institution

# of Researchers on Study per Institution

An Investigation into the Potential Roles of Vasoactive Intestinal Peptide and Substance P in the Pathophysiology of Plastic Bronchitis and Protein Losing Enteropathy in Children with Palliated Single Ventricle Physiology  MCW 4
CHW 1
Assessment of the Benefits, Risks, and Costs of Neonatal Screening for Cystic Fibrosis CHW* 3
UW-Madison 1
Assessment of the Contribution of Platelet TFPI to the Severity of Bleeding in Patients with Hemophilia: Phase II CHW 1
BCW 1
Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression Trial - EXTended criteria donors (BENEFIT-EXT) Clinical Protocol IM103027 MCW 5
CHW 1
Biomechanics of Gait in Patients Treated for Femoroacetabular Impingement (FAI)  MCW 2
Marquette Univ 1
Brain Activation and the Stress Response during Motor Performance in Older Adults MCW 2
Marquette Univ 4
Bridging the Gap Between Patient Perception of Quality & the Engineering Performance of Assistive Lower Limb Prostheses MCW 1
Marquette Univ 2
Deoxyguanosine monophosphate (dGMP) and Deoxyadenosine monophosphate (dAMP) Treatment for DGUOK Deficiency CHW* 1
Med. Univ of S. Carolina 1
Development of a prototype, fuzzy logic-based mobile application and web interface for self management of T2DM MCW 1
VA** 1
MSOE 1
UW-Milwaukee 1
Effect of Adenosine 2A Receptor Agonist Regadenoson on Microvascular Blood Flow in Sickle Cell Anemia  MCW 1
CHW 1
BCW 3
Effects of Altered Perfusion on Neuromuscular Fatigue and Leg Function Post Stroke  MCW 1
Marquette Univ 1
Fibrocytes in Sickle Cell Disease CHW* 4
BCW 1
fMRI and Robot-Assisted Practice of Activities of Daily Living MCW 2
Marquette Univ 1
fMRI and Robot-Assisted Practice of Activities of Daily Living: Case Studies MCW 5
Marquette Univ 1
fMRI Database and Registry MCW 4
Marquette Univ 1
UW-Milwaukee 1
fMRI of the Person Identity Network: Aging and APOE MCW 2
Marquette Univ 1
UW-Milwaukee 2
Gender differences in the effects of insulin resistance in African Americans plus survey, Factors Affecting AA Participants in Clinical Research MCW 5
CHW 1
Genetic Analysis Of Children With And Without Inflammatory Bowel Disease (IBD) CHW 3
Emory Univ 1
Genetic Basis of Hemangiomas MCW 1
CHW 2
Genetic Modifiers in Cystic Fibrosis MCW 1
CHW 1
Genetic Studies of Human Development Disorders MCW 1
CHW 1
Human Brain Imaging during Locomotion MCW 2
Marquette Univ 4
Intrauterine and Perinatal Bisphenol-A and Neonatal Body Composition CHW 5
UW-Milwaukee 1
Mapping the Effects of the KIAA0319 Dyslexia Susceptibility Gene on the Neural Substrates of Reading  MCW 3
CHW 1
UW-Milwaukee 1
Measuring Body Composition with Spina Bifida: A Pilot Study CHW* 3
Marquette Univ 1
UW-Milwaukee 1
Million Veteran Project MCW 1
VA** 1
Molecular Variants Causing von Willebrand Disease MCW 1
CHW 3
BCW 1
MOVE OUT: A partnership with veterans groups to enhance weight management in VHA MCW 4
VA** 1
Mpex 207: A Phase 3, Multi-Center, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MP 376 (Levofloxacin Inhalation Solution; Aeroquin) in Stable Cystic Fibrosis Patients MCW 1
CHW 4
Mpex 209: A Phase 3, Open-Label, Randomized Trial to Evaluate the Safety and Efficacy of MP-376 Inhalation Solution (Aeroquin) Versus Tobramycin Inhalation Solution (TIS) in Stable Cystic Fibrosis Patients MCW 1
CHW 4
Osmotic Threshold for Thirst and Vasopressin Secretion in Stone Formers MCW 3
VA** 1
Pathophysiological Mechanisms in Type I vWD MCW 1
CHW 3
BCW 1
Photodynamic Therapy (PDT) for Brain Tumor Dispersal MCW 4
CHW 1
Red Blood Cell Adherence to Vascular Endothelium in Sickle Cell Disease CHW* 1
BCW 1
Safety of Adenosine 2AA Agonist Lexiscan in Children and Adults with Sickle Cell Disease MCW 1
CHW 4
BCW 1
Self-management Guided Discharge Teaching for Parents of Hospitalized Children: A Pilot Study (Short title = The Discharge Study) CHW 3
Marquette Univ 1
UW-Milwaukee 1
Shoulder Tendinopathy in Diabetic Patients MCW 2
VA** 2
The Aging Brain: Imaging Genetics of Brain Structure and Function MCW 1
UW-Milwaukee 1
The effect of combining prebiotic treatment with a diet/physical activity educational program on body composition and intestinal microbiota among predominately overweight and obese children  CHW 2
Marquette Univ 1
The Effect of Tailored Step-Count Feedback on Vascular Homeostasis and Cardiovascular Performance in the Patients with and without underlying coronary artery disease MCW 4
UW-Milwaukee 1
The effects of exercise on brain function and metabolic profile in dementia: a collaborative pilot clinical trial MCW 3
Marquette Univ 1
UW-Milwaukee 2
Use of FMRI to Study Brain Activation following Rectal Stimulation in Children with IBD MCW 1
CHW 3
Vascular Function Data Bank MCW 5
UW-Milwaukee 1
Working with Veterans Organizations to Improve Blood Pressure (POWER) MCW 3
VA** 1
A Novel Target for the Treatment of Schizophrenia Concordia 2
Marquette Univ 1
Rogers Memorial 1
Assessment and Prevention of Acute Kidney Injury Following Cardiopulmonary Bypass in Children Through Novel Application of Serum and Urine Biomarkers MCW 4
Biomarkers in Diastolic Dysfunction/Heart Failure with Preserved Ejection Fraction MCW 2
Bridging the Gap between Patient Perception of Quality and the Engineering Performance of Assistive Lower Limb Devices Marquette Univ 4
MCW 1
Changes in BMI and Intestinal Microbiota with Prebiotics, Probiotics and Symbiotics Marquette Univ 1
MCW 1
Computational Analysis of Transcranial Magnetic Stimulation Marquette Univ 1
MCW 1
Establishing a Cellular Basis for fMRI Brain Mapping and Visual/Motor Protheses Through Optogenetic Brain Stimulation MCW 2
UW-Milwaukee 1
Ex Vivo Thermoacoustic Imaging of Prostate Cancer Marquette Univ 1
MCW 3
Image-guided Proteomics of Glioblastoma Multiforme - Moving Towards Personalized Medicine MCW 3
Mechanisms of Anti-microbial Effect of Blue Light on Methicillin Resistant Staphylococcus Aureus (MRSA) MCW 1
UW-Milwaukee 2
Neural Mechanisms Underlying Functional Laterality of the Intact Arm of Upper-limb Amputees - An fMRI Study MCW 1
UW-Milwaukee 1
Parent-Child Interaction in a Motor and Communication Intervention for Toddlers with Down Syndrome UW-Milwaukee 3
Preclinical Study to Optimize Anti-tumor Immune Activation Against Neuroblastoma, Breast Cancer & Multiple Myeloma using a Cell-based Tumor Vaccination in Combination with Immune Modulating Agents MCW 6
Role of IgA and IgM Immunoglobulins in Heparin-induced Thrombocytopenia and Thrombosis (HIT) BCW 3
MCW 2
Role of Sensory Enhancement on Hand Motor Control and Functional Recovery After Stroke - an fMRI Study Marquette Univ 1
MCW 2
UW-Milwaukee 2
Serum Endocannabinoid Concentration and Salivary Cortisol in Patients with Cyclic Vomiting Syndrome (CVS) MCW 3
The Role of SDF-1/CXCR4 Axis in Migration and Repair Capacity of Mesenchymal Stem Cells Transplanted in In Vitro Model of Traumatic Brain Injury MCW 2
Treating Patients' "Real" Avatars in Virtual Medical Offices Ashland University 1
MCW 1
UW-Milwaukee 2

* Primary CHW investigator has faculty appointment at MCW
** Primary investigator has joint appointment MCW & VA

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