MCW Cardiovascular Center Genetic and Molecular Etiology of
Congenital Heart Disease Affinity Group


The Cardiovascular Center has initiated AFFINITY GROUPS to stimulate and foster greater interaction and collaborations between CVC investigators and other investigators from MCW departments and outside institutions, such as Marquette University, the University of Wisconsin Milwaukee and the University of Georgia.


This group includes Aoy Tomita-Mitchell, PhD, and Michael E. Mitchell, MD, who are interested in identifying genetic risk factors of heart malformations and in understanding how these genetic alterations impact pathways at the molecular level. The group hopes to be able to improve immediate and long-term outcomes for patients with congenital heart disease (CHD) by identifying patients at risk for CHD before their heart fails. Ultimately, the group hopes that by identifying the genes and the pathways that are altered in CHD, therapies that will repair these pathways can be targeted. To reach this goal, this laboratory is focused on the following:Heart

  1. Patient recruitment to a CHD Tissue and DNA Bank, a repository of DNA and surgical discards from patients with congenital heart disease.
  2. The development and utilization of high-throughput genetic technologies in order to reduce the high costs of performing large-scale genetic studies.
  3. The integration of genetic information with clinical variability and outcomes.

Cardiovascular Annual Report 2010

For general research information about the MCW Cardiovascular Center:

Kelly J. Duffy, PhD
Academic Program & Research Consultant
(414) 955-2578 | kduffy@mcw.edu

Department of Medicine/Cardiology and the MCW Cardiovascular Center
Medical College of Wisconsin
8701 Watertown Plank Rd.
Milwaukee, WI 53226-0509

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
414-955-8296
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