MCW Cardiovascular Center Affinity Groups

Affinity groups (AGs) of the CVC have been redesigned to organize collaborative networks and to promote interactions among investigators with common and disease-oriented research interests. Accordingly, all AGs will continue to serve as campus incubators in order to stimulate, exchange and nurture new ideas and develop novel research programs in basic, translational, and clinical research.

An essential requirement, however, is that the AGs become organized as launching platforms to becoming "signature" clinical and research programs. By design, signature programs (SPs) are disease-oriented research programs, which are inclusively geared to transcend the chasm and to create opportunities from across MCW and all regional affiliated programs (e.g., Blood Research Institute, Children Hospital of Wisconsin, Froedtert Health Systems, etc.). A formal affiliation with the CVC will not preclude scientists and clinical colleagues forging new collaborations that are dedicated to achieving the new objectives outlined below for the group.

First, the size and composition of the working groups should contain investigators and clinician scientists/investigators who form critical alliances to enable the these working groups to become the nucleus for a Program Project Grant, multiple PI/PD and multidisciplinary (U01) grants.

Second, AGs meeting these criteria will be eligible for support for an 'off-site' retreat and, perhaps, institutional seed grant funding administered jointly between the CVC and Departments. Specific details for these competitive awards will be provided when funds become available.

This evolution of AGs should not discourage small groups of individuals functioning as extended lab meetings/journal clubs of labs working on interrelated problems. However, we believe these efforts for reorganization of AGs should accelerate the testing of new ideas in translational and health outcomes research while enhancing the success rate of research programs for extramural funding.



MCW investigators interested in attending meetings of one of these groups should contact the group organizer.



Atheroslerosis (Daisy Sahoo, 955-7414)
Organize a group fostering collaborative work to improve R01 grant content.
Composition: K. Pritchard, D. Sahoo
Scheduled on an ad-hoc basis; contact Daisy Sahool for details

Cardiac Function and Remodeling (Paul Goldspink, 955-7575)
To foster collaborative research centered around the theme of cardiac function and remodeling in disease and injury. To develop interdisciplinary approaches to improving cardiac function with the goal of enhancing funding opportunities.
Composition: J. Auchampach, P. Goldspink, R. Ramchandran, J. Strande
Scheduled once per month on a Wednesday from 12 – 2 p.m.; contact Paul Goldspink for details

Congenital Heart Disease: Genetic Etiology and Risk Factors (Aoy Tomita-Mitchell, 955-2355)
Lab meeting discussing lab techniques: capillary electrophoresis, real-time PCR, TaqMan, Affy chip analysis, Tissue Bank handling, sequence capture.
Composition: M. Mitchell, A. Tomita-Mitchell, D. Woodrow Benson
Scheduled first Monday of each month, 10 – 11 a.m., CRI Second Floor, Room C2145

Free Radicals and Vascular Function (David Harder, 955-2203)
Develop a PPG on mechanisms of reactive oxygen species in vascular signaling.
Composition: J. Corbett, D. Gebremedhin, D. Gutterman, D. Harder, N. Hogg, K. Pritchard, J. Vasquez-Vivar
Scheduled weekly on Thursdays, 4 – 5 p.m., CVC Conference Room, M4799

Hypertension (Allen Cowley, 955-8277)
Integrate hypertension research at MCW and foster better communication among scientists working in the field.
Composition: A. Cowley, A. El-Meanawy, A. Greene, J. Imig, M. Liang, J. Lombard, D. Mattson, P. O'Connor, E. Saad, A. Sorokin, A. Starushchenko, C. Williams
Scheduled second Wednesday of each month, 10 – 11 a.m., CVC Conference Room, H4950

Microvascular Function (Andreas Beyer, 955-7514)
Joint lab meetings and Journal Club.
Composition: A. Beyer, D. Gutterman, M. Widlandsky, D. Zhang
Scheduled weekly on Mondays, 3 – 4 p.m., CVC Conference Room, H4950

Pulmonary (Elizabeth Jacobs, 384-2000, x41430)
PPG
Composition: D. Frank, E. Jacobs, G. Konduri, M. Medhora, M. Merker, R. Molthen, K. Pritchard
Scheduled on an ad-hoc basis; contact Laura Adrian for details

Regenerative Medicine (John Lough, 955-8459)
Research progress updates.
Composition: J. Auchampach, S. Duncan, J. Lough, R. Misra, P. North, M. Zhao
Scheduled monthly; contact John Lough for details

Vascular Biology (Ramani Ramchandran, 955-2387)
Alternate Journal Club and research presentation.
Composition: K. Duffy, R. Miao, R. Misra, R. Ramchandran, R. Sood, R. Teng, M. Woodnicka
Scheduled weekly on Thursdays, 11 a.m. – noon; Room C3195

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(414) 955-8296
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